Hu, ZhenxiangWang, ShengfuNie, Linfei2023-05-192023-05-192023-01-24Hu, Z., Wang, S., & Nie, L. (2023). Dynamics of a partially degenerate reaction-diffusion cholera model with horizontal transmission and phage-bacteria interaction. Electronic Journal of Differential Equations, 2023(08), pp. 1-38.1072-6691https://hdl.handle.net/10877/16843We propose a cholera model with coupled reaction-diffusion equations and ordinary differential equations for discussing the effects of spatial heterogeneity, horizontal transmission, environmental viruses and phages on the spread of vibrio cholerae. We establish the well-posedness of this model which includes the existence of unique global positive solution, asymptotic smoothness of semiflow, and existence of a global attractor. The basic reproduction number R0 is obtained to describe the persistence and extinction of the disease. That is, the disease-free steady state is globally asymptotically stable for R0≤1, while it is unstable for R0>1. And, the disease is persistence and the model has the phage-free and phage-present endemic steady states in this case. Further, the global asymptotic stability of phage-free and phage-present endemic steady states are discussed for spatially homogeneous model. Finally, some numerical examples are displayed in order to illustrate the main theoretical results and our opening questions.Text38 pages1 file (.pdf)enAttribution 4.0 InternationalCholera modelEnvironmental and horizontal transmissionSpatial heterogeneity and phagesBasic reproduction numberGlobal asymptotic stabilityArticle