Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
dc.contributor.author | Cantu, Travis | |
dc.contributor.author | Rodier, Bradley | |
dc.contributor.author | Iszard, Zachary | |
dc.contributor.author | Kilian, Alissa | |
dc.contributor.author | Pattani, Varun P. | |
dc.contributor.author | Walsh, Kyle | |
dc.contributor.author | Weber, Katharina | |
dc.contributor.author | Tunnell, James | |
dc.contributor.author | Betancourt, Tania | |
dc.contributor.author | Irvin, Jennifer A. | |
dc.date.accessioned | 2020-05-26T16:59:14Z | |
dc.date.available | 2020-05-26T16:59:14Z | |
dc.date.issued | 2016-01 | |
dc.description.abstract | A method for the synthesis of electroactive polymers is demonstrated, starting with the synthesis of extended conjugation monomers using a three-step process that finishes with Negishi coupling. Negishi coupling is a cross-coupling process in which a chemical precursor is first lithiated, followed by transmetallation with ZnCl2. The resultant organozinc compound can be coupled to a dibrominated aromatic precursor to give the conjugated monomer. Polymer films can be prepared via electropolymerization of the monomer and characterized using cyclic voltammetry and ultraviolet-visible-near infrared (UV-Vis-NIR) spectroscopy. Nanoparticles (NPs) are prepared via emulsion polymerization of the monomer using a two-surfactant system to yield an aqueous dispersion of the polymer NPs. The NPs are characterized using dynamic light scattering, electron microscopy, and UV-Vis-NIR-spectroscopy. Cytocompatibility of NPs is investigated using the cell viability assay. Finally, the NP suspensions are irradiated with a NIR laser to determine their effectiveness as potential materials for photothermal therapy (PTT). | |
dc.description.department | Chemistry and Biochemistry | |
dc.description.department | Materials Science, Engineering, and Commercialization | |
dc.format | Text | |
dc.format.extent | 13 pages | |
dc.format.medium | 1 file (.pdf) | |
dc.identifier.citation | Cantu, T., Rodier, B., Iszard, Z., Kilian, A., Pattani, V., Walsh, K., Weber, K., Tunnell, J., Betancourt, T., & Irvin, J. (2016). Electroactive polymer nanoparticles exhibiting photothermal properties. Journal of Visualized Experiments(107), e53631. | |
dc.identifier.doi | https://doi.org/10.3791/53631 | |
dc.identifier.uri | https://hdl.handle.net/10877/10313 | |
dc.language.iso | en | |
dc.publisher | Journal of Visualized Experiments | |
dc.rights.holder | © 2016 Journal of Visualized Experiments. | |
dc.source | Journal of Visualized Experiments, 2016, No. 107, Article e53631. | |
dc.subject | engineering | |
dc.subject | electroactive polymers | |
dc.subject | conductive polymers | |
dc.subject | negishi coupling | |
dc.subject | electrochemistry | |
dc.subject | nanoparticles | |
dc.subject | emulsion polymerization | |
dc.subject | photothermal therapy | |
dc.title | Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties | |
dc.type | Article |
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